摘要
本文应用双抗体夹心直接ELISA法对36例胃癌患者血清SIL－2R水平进行了测定。胃癌患者血清SIL2R水平明显高于正常人群（p＜0．01）及慢性良性胃病患者（p＜0．01）；Ⅲ～Ⅳ期患者血清SIL-2R水平明显高于Ⅰ～Ⅱ期患者（p＜0．01）；胃癌根治术后10天血清SIL-2R水平较术前明显下降（p＜0．01），与正常人群对照无明显差异（p＞0．05）。结果说明血清SIL-2R测定可作为胃癌的诊断、疗效观察和预后评价的一项有价值的指标。
Serum SIH-2R levels in 36 patients with gastric cancer were detected by using a sandwich ELISA.The results showed that the mean level of serum SIL-2R of gastric cancer patients was much higher than that ofhealthy subjects (p<0.01) and that of benign disoniers (p<0.01). Serum SIL-2R levels of stage Ⅲ～Ⅳ patients weresignificantly higher than that of stuge Ⅰ～Ⅱ patients (p<0.01). Serum SIL-2R level decreased sigllificantly at 10dags after radical surgery for gastric cancer (p<0.01). It can be concluded that serum SIL-2R a8say is a new bio-logical marker for the assessment of the stage, the response to medical intervention and the prognosis in gastriccancer.
