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肺癌患者诱导痰中端粒酶活性检测的临床意义

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摘要 目的评价端粒酶活性在肺癌患者诱导痰中表达的临床意义。方法采用TRAP-PCR-ELISA法对30例肺癌患者诱导痰、自然痰及15例肺部良性病变者诱导痰中端粒酶活性进行测定。结果肺癌患者的诱导痰、自然痰以及非肺癌患者诱导痰中的端粒酶阳性率和OD值分别为80.0%、56.7%、13.3%和0.523±0.267、0.349±0.247、0.091±0.110。肺癌诱导痰组高于自然痰组及良性对照组,差异有显著性(P<0.01)。结论诱导痰中端粒酶活性的检测有助于肺癌的诊断及其与肺部良性疾病的鉴别诊断,且优于自然痰。
出处 《江西医学院学报》 2006年第2期137-139,共3页 Acta Academiae Medicinae Jiangxi
基金 江西省卫生厅课题(20041139)
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参考文献4

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