2[1]Potter JJ, Womak L, Mezey E, et al. Transdifferentiation of rat hepaic steuate cells results in leptin expression[J]. Biochem Biophys Res commun, 1998, 244:178 - 182.
3[2]Collins S, Kuhn CM, Petro AE, et al. Role of leptin in fot regulation[J]. Natur, 1996, 380:677.
4[3]Nemec ZM, Preininger K, Englisch R, et al. Acute effect of leptin on hepatic glycogenolysis and gluconeogenesis in perfused rat liver[ J ]. Hepatology, 1999, 29:166 - 172.
5[4]C hehab FF, Lim ME, Lu R. Correction of the sterility defect in homozygous obesefemale mice by treatment with the human recombinant leptin[J]. Nat Genet, 1996, 12:318.
6[5]Tobe K, Ogura J, Tsukamotoc, et al. Relationship between serum leptin and fatty liver in Japnese male adolescent university students [J] .Am J Gastroenterol, 1999, 94(11) :3328 - 3335.
7[6]Lin HZ, Yang SQ, Chuckaree C, et al, Metformin reverses fatty liver disease in obese, leptin - deficient mice[J]. Nat -Med, 2000,6(9) :998 - 1003.
8[7]Faggioni R, Jones - Carson J, Reed DA, et al leptin - deficient(ob/ob) mice are protected from T cell mediated hepatotoxicity: role of tumor necrosis factor alpha and IL- 18[J] .Proc Natl Acad Scir USA, 2000, 97(5) :2367 - 2372.
9[8]GianniniE, Botta F, CataldiA etal. Leptin levels in nonalcoholic steatohepatitis and chronic hepatitis C [J]. Hepatogastroenterology,1999, 46(28): 2422 - 2425.
10[9]Ikejima K, Honda H, Takei Y, et al. Hepatic stelate cells produce leptin during the progression of liver fibrosis[J]. Heptology, 1999,30: 492A.
