摘要
采用流式细胞仪检测早期Graves眼病(GO)组、非突眼Graves病(GD)组和正常对照组的T细胞亚群、IFN-γ^+T细胞和IL-4^+T细胞。结果显示早期GO存在T细胞亚群失衡,以CD_4^+Th1细胞介导的细胞免疫为主。
T cell subsets, the IFN-γ^+ T lymphocyte (represent Th1-like cytokines) and the IL-4^+ T lymphocyte (represent Th2-like cytokines ) were assayed by flow cytometry in patients with early Graves' ophthalmopathy (GO), patients with initial Graves' disease (GD) without ophthalmopathy and normal subjects. There was an imbalance of T cell subsets during early GO. The Th1-type CD4^+ T cell-mediated immunity might play a predominant role in the pathogenesis of early GO.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2006年第2期126-127,共2页
Chinese Journal of Endocrinology and Metabolism