正柴胡饮抗病毒作用的实验研究

Experimental Study on Antiviral of Zheng Chaihu Yin(Orthodox Radix Bupleuri Granule)

对正柴胡饮的体内、体外抗病毒作用进行了研究。实验结果表明，在体外，正柴胡饮４ｍｇ／ｍｌ对所试属于ＲＮＡ型的副流感病毒等６种、属于ＤＮＡ型的单纯疱疹病毒等３种病毒的致细胞病变有抑制作用；在体内，对流感病毒ＦＭ１感染小鼠所致肺病变有显著的抑制作用，并能显著降低流感病毒在小鼠肺内的增殖量。

Antiviral effect of Zheng Chaihu Yin(ZCHY)was studied in vitro and in vivo. Exper-imental data showed that 4mg/ml of ZCHY could inhibit the cytopathic effect induced by parain-fluenza and other 5 strains of RNA virus in vitro. ZCHY also inhibited the pulmonary consolidation and virus multiplication in pneumonic mice infected with FMi strain of influenza virus.