树枝状大分子在药物领域的应用研究进展

Dendrimers application in drug fields

树枝状大分子是一类高规整度、具有纳米尺度、三维结构的树枝状大分子,其结构和分子尺寸大小具有良好的可控性。树枝状大分子的大小呈线性增长,而外层功能化基团呈级数增长。因此树枝状大分子的功能化备受人们的关注。而其作为药物载体已成为当今研究热点之一。作者仅就树枝状大分子在药物领域中的应用研究进展作简要综述。

Dendri-mers are a group of highly ordered, three-dimensional, treelike functional polymers. Dendrimers are monodisperse macromolecules and they have well-defined structure, controlled surface functionality and size. Dendrimer size increases linearly and the number of surface functional groups increases exponentially with generation number. So functionalization of dendrimers attracts scientists＇ interest. And the using of them as drug carriers is one of the focuses of current research. In this review we just summarize their uses in drug research field.