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MiniSTR技术的研究进展 被引量：10

Recent Advancement in MiniSTR Research
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摘要 短串联重复序列(STR)是法医DNA鉴定中最常用和最重要的遗传标记,但是对于降解和微量的DNA样品,经常得不到完整的DNA分型甚至分型失败。MiniSTR技术通过设计更靠近重复序列的引物,得到更短一些的STR基因座,提高了降解和微量检材的DNA分型成功率。本文综述了miniSTR技术的研究进展,以服务于法医学实践。 As the most popular and important inherited marker used in forensic identification, short tandem repeat （STR） always have partial DNA profiling or even no results when handling degraded or minute DNA sample. Through redesigning primers close to STR core repeats, MiniSTR can access shorter STR loci and increase success rate of DNA profiling in degraded or minute DNA sample. The review provides an update on the advancement of miniSTR research to give information in the practice of forensic science.
作者 王会品 刘超 孙宏钰
机构地区 中山大学基础医学院法医学系 广州市刑事科学技术研究所
出处 《法医学杂志》 CAS CSCD 2006年第2期159-160,I0001,I0002,共4页 Journal of Forensic Medicine
关键词 MINISTR 降解DNA 法医DNA分型 miniSTR degraded DNA forensic DNA profiling
分类号 R394 [医药卫生—医学遗传学] R392.2 [医药卫生—免疫学]
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参考文献20

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法医学杂志
2006年 第2期

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