抗心磷脂抗体与偏头痛关系的研究

RELATION OF ANTIPHOSPHOLIPID ANTIBODIES TO MIGRAINE

为了探讨抗心磷脂抗体（ＡＣＡ）与偏头痛的关系，用ＥＬＩＳＡ法分别对７５例偏头痛患者和正常人测定血清抗心磷脂抗体。结果表明偏头痛组和正常对照组ＡＣＡ阳性率分别为３２％和２．６７％，差异显著（Ｐ＜０．０１）；另外还发现ＡＣＡ阳性的偏头痛患者无性别差异。这提示ＡＣＡ与偏头痛有关，并对ＡＣＡ激发偏头痛的机理进行了探讨。

In order to explore the role of antiphospholipid antibodies(ACA) to migraine l ACAwere examined in 75 patients with migraine by enzyme一linked immunosorbent assay(ELISA)methodand the resuIts were compared with those of 75 normal controls,The results showed that elevated titersof ACA in migraine patients and controls are 32%and 2.67%respectively.It is indicated that ACA arestrongly associated with an immunomediated migraine,The pathogenetic mechanism was also discussed.