静滴蝮蛇抗栓酶和硝酸甘油治疗不稳定性心绞痛疗效观察

Observation on the Curative Effect of Unstable Angina Pectoris Treated with intravenous Drip of Agkistrodon Halys Streptokinase

本文报告经静滴蝮蛇抗栓酶和硝酸甘油治疗不稳定性心绞痛３２例（治疗组）并与常规方法治疗的不稳定性心绞痛２０例（对照组）进行对比观察。结果表明，治疗组缓解率为９３．８％，心电图有效率９０．６％，均优于对照组（Ｐ＜０．０１）。蝮蛇抗栓酶具有抗凝和增强纤溶系统活性的作用，硝酸甘油可降低冠脉阻力并改善心肌血流，故两药联用静滴，其近期和远期疗效均较确切、安全。同时，也可作为急性心肌梗塞二级预防的一项积极有效的措施。

Compared with 20 cases in the control group, 32 cases of unstable angina pectoris treated with intravenous drip of Agkistrodon halys streptokinase and nitroglycerin in the therapeutic group were studied. The results showed that the Agkistrodon halys streptokinase had anticoagulational effect and could increase the activity of fiber dissolution system.halys streptokinase had anticoagulational effect and could increase the activity of fiber dissolution system. The nitroglycerin could reduce the resistance of cornary arteries and improve the conditions blood vessels. Both short and long term of curative effects of the patients treated with two medicines were safe and reliable. And it could be a good method to avoid the occurance of myocardiac infarction.