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铂类化疗药耐药机制的分子基础及新观点 被引量:2

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摘要 过去对铂类药物耐药机制分子基础的研究主要集中在细胞凋亡抑制、信号转导及相关癌基因的过表达等方面。近几年已有了一些新的阐释,如胞膜蛋白、细胞间缝隙连接及肿瘤微环境的改变等。这不仅为认识铂类化疔药耐药机制开拓了视野,也为肿瘤的临床治疗提供了新的途径。
出处 《国际肿瘤学杂志》 CAS 2006年第4期256-258,共3页 Journal of International Oncology
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