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氮杂内酯类抗生素研究现状 被引量：2

Development of Azalide Antibiotics
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摘要 综述大环内酯类抗生素的发展及作用机制以及氮杂内酯类抗生素的结构修饰与构效关系研究进展。作为新一代半合成大环内酯类衍生物,氮杂内酯具有抗菌谱广、药物动力学性质优良等特点。 The development and mechanism of action of macrolide antibiotics and the researches on structure modification and structure-activity relationship of azalides in recent years were reviewed. Azalides are the new generation semi-synthetic macrolides with a broad-spectrum and strong antibacterial activity and better pharmacokinetics behavior.
作者 张涛 姜凤超
机构地区 华中科技大学同济医学院药学院
出处 《药学进展》 CAS 2006年第4期150-157,共8页 Progress in Pharmaceutical Sciences
关键词 大环内酯 氮杂内酯 作用机制 结构修饰 耐药性 Macrolides Azalides Mechaism of action Structure modification Drug resistance
分类号 R978.1 [医药卫生—药品]
  • 相关文献

参考文献32

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共引文献3

同被引文献17

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药学进展
2006年 第4期

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