妊娠梅毒85例临床分析

Clinical Analysis of 85 Pregnant Syphilis Women

目的探讨改善妊娠期梅毒的妊娠结局和围产儿预后的方法。方法将85例妊娠期梅毒患者分为治疗组和未治疗组,比较两组孕妇的妊娠结局和梅毒儿的发生情况。结果治疗组的足月妊娠率达81.32%,早产、死胎发生率分别为1 6.9 8%和1.8 9%,两组妊娠结局有显著性差异(P<0.0 5)。治疗组、未治疗组梅毒儿的发生率分别为23.08%和72.00%,两组比较有显著性差异(P<0.05)。结论妊娠期梅毒患者及早的、规范的驱梅治疗可以明显改善妊娠结局和围产儿预后,降低梅毒儿的发生;应该对高危人群进行性健康教育和梅毒血清学筛查。

Objective To investigate the methods of improving the outcome of pregnant women with syphilis and the prognosis of perinatal. Methods 85 pregnant women with syphilis by serological assays were divided into two groups. The pregnant outcomes and congenital syphilis were compared between two groups. Results In treated group,term delivery reached 81.32%, and the rate of premature birth and fetal intrauterine death were 16.98% andl. 89% ,which were significantly better than their in untreated group （P 〈 0.05 ）. The rate of congenital syphilis was 23.08% in treated group, which was significantly lower than that in untreated group（ P 〈 0.05 ）. Conclusion Regular and early treatment to pregnant women with syphilis could significantly improve the outcome of pregnancy and the prognosis of perinatal, and also could decrease the incidence of congenital syphilis. The education of sex and syphilis by serological assays in screen was very critical among high-risk pregnant women.