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妥泰的临床应用研究进展 被引量：3

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摘要 妥泰作为一种新型广谱抗癫痫药物,临床上不仅用于治疗各种类型癫痫,同时还具有神经保护作用和用以治疗神经痛、减肥、特发性震颤、双相情感障碍、戒酒、面肌痉挛以及偏头痛等。
作者 何继红 孙红斌
机构地区 四川省医学科学院.四川省人民医院神经内科
出处 《国际神经病学神经外科学杂志》 2006年第2期153-156,共4页 Journal of International Neurology and Neurosurgery
关键词 妥泰 癫痫 神经痛 戒酒 减肥 特发性震颤 抗癫痫药物
分类号 R96 [医药卫生—药理学]
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参考文献19

  • 1Chriatensen J, Andreasen F, Poulsen JH, et al, Randomized,concentration-controlled trial of topiramate in refractory focal epilepsy. Neurology, 2003, 61 (9) : 1210-1218.
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  • 4Christensen J, Andreasen F, Poulsen JH, et al. Randomized,concentration-controlled trial of topiramate in refractory focal epilepsy. Neurology, 2003, 61(9) : 1210-1218.
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  • 6Groselj J, Guerrini R, Van Oene J, et al. Experience with topiramate monotherapy in elderly patients with recent-onset epilepsy. Acta Neurol Seand, 2005, 112(3) : 144-150.
  • 7Donofrio PD, Raskin P, Rosenthal NR, et al. Safety and effectiveness of topiramate for the management of painful diabetic peripheral neuropathy in an open-label extension study, Clin Ther, 2005, 27(9) : 1420-1431.
  • 8Raskin P, Donofrio PD, Rossenthal NR, et al, Topiramate vs placebo in painful diabetic neuropathy: An',dgesic and metabolic effects. Neurology. 2004, 63(5) : 865-873.
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二级参考文献4

共引文献2

同被引文献33

  • 1黄静,任榕娜,陈新民,叶礼燕.抗癫癎药妥泰对幼鼠肝毒性的实验研究[J].中国当代儿科杂志,2007,9(1):54-58. 被引量：3
  • 2林华,吴立文,黄远桂,陈云春,温晓妮.海马苔藓纤维出芽及突触重组与颞叶癫痫的相关性研究[J].中华医学杂志,2007,87(5):341-344. 被引量：5
  • 3Rosenfeld WE, Liao S, Kramer LD, et al. Comparison of the steady-state pharmacokinetics of topiramate and valproate in patients with epilepsy during monntherapy and concomitant therapy. Epilepsia, 1997, 38(3) : 324 -333.
  • 4Latour P, Biraber A, Polard E, et al. Drug induced enceph- alopathy in six epileptic patients: topiramate? vatproate? or both? Hum Psychopharmacol, 2004, 19(3) : 193-203.
  • 5Mimrod D, Specchio LM, Britzi M, et al. A comparative study of the effect of carbamazepine and valproiee acid on the pharmacokinetics and metabolic profile of topiramate at steady state in patients with epilepsy. Epilepsia, 2005 , 46 ( 7 ) : 1046-1054.
  • 6Steinborn B. Pharmaeokinetic interactions of carbamazepine with some antiepileptic drugs during epilepsy treatment in chldren and adolescents. Rocz Akad Med Bialvmst, 2005, (suppl 1):9-15.
  • 7Gisclon LG, Curtin CR, Kramer LD. The steady-state (ss) pharmacokinetics ( PK ) of phenytoin ( Dilantin ) and topiramate in epileptic patients on monotherapy, and during combination therapy. Epilepsia, 1994, 35 ( Suppl 8 ) : 54-55.
  • 8Luszczki JJ, Czuczwar SJ. Gapaentin syrergistically interacts with topiramate in the mouse maximal electroshock seizure model: an isobolographic analysis. Pharmacological Rep, 2006, 58(16) : 944-954.
  • 9Luszczki JJ. lsobolographic analysis of interaction between drugs with nonparallel does-respose relationship curves: a practical application. Naunyn Schmiedebergs Arch Pbarmacol, 2007, 375(2) : 105-114.
  • 10Doose DR, Brodie MJ, Wilson EA, et al. Topiramate and lamotrigine pharmaeokinetics during repetitive monotherapy and combination in epilepsy patients. Epilepsia, 2003 , 44 ( 7 ) : 917-922.

引证文献3

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国际神经病学神经外科学杂志
2006年 第2期

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