膳食营养素摄入对人血清载脂蛋白A-IV水平的影响

Effect of dietary fat intake on human serum apolipoprotein A-IV levels

目的:探讨膳食摄入对血清apoA-IV水平的影响,以进一步阐明apoA-IV调节摄食和能量平衡的作用机理。方法:选取山东省淄博市农村和济南市社区居民389例,采用酶联免疫吸附法(ELISA)检测空腹12 h血清apoA-IV的水平;采用3 d膳食记录法获得膳食摄入量。所有数据使用SPSS12.0版软件进行分析。结果:apoA-IV水平与脂肪、膳食纤维、碳水化合物、蛋白质摄入量呈负相关关系(P<0.05),高脂膳食者血清apoA-IV水平显著低于低脂膳食者(P<0.05)。结论:高脂肪摄入是影响血清apoA-IV水平的主要因素。

Objective： To investigate the effect of dietary fat intake on human serum apolipoprotein（ape） A-Ⅳ levels and further illustrate the regulation of food intake and bodyweight gain. Methods： This investigation was conducted in 389 subjects aged 7-70 years from Zibo and Jinan city in Shandong Province. The serum apoA-Ⅳ concentrations were measured by enzyme-linked immunosorbant assays （ELISA）. Dietary intake was estimated from 3-day food record. Statistical analyses were performed with SPSS 12.0. Results： Senan apoA-Ⅳlevels were negatively correlated with dietary fat, fiber, carbohydrate, and protein intake（P 〈0.05）. Humans chronically consuming a highfat diet initially developed significantly lower serum apoA-Ⅳ levels than those of a low-fat diet. Conclusion： A highfat diet intake is the primary factor to affect serum apoA-Ⅳ levels.