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经皮冷消融治疗局部进展型非小细胞肺癌 被引量:7

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摘要 目的:探讨氩氦冷消融技术治疗局部进展型肺癌的有效性和安全性。方法:120例非小细胞性肺癌患者接受经皮冷消融治疗,随访时间超过2年。采用氩氦消融系统,在B超或CT引导下,将穿刺导管经皮插入肿瘤中心进行冷消融。结果:治疗后症状改善率胸痛为78.5%,咯血79.2%,咳嗽69.1%,呼吸困难72.0%。症状改善持续时间1 ̄21个月,中位13个月;治疗后3个月,有CT复查资料者98例中,CR25例(25.5%),PR41例(41.8%),MR21例(21.4%),NC11例(11.2%);有48例(40%)在随访期出现肿瘤复发,12例(10%)在肺外出现转移灶。目前仍生存的84例中,最长已生存24个月。生存率:6个月64%,12个月55%,18个月44%,24个月36%。2例并发气胸,4例并发血胸,5例并发肺部感染,经对症处理后消失。结论:对于不能手术切除的局部进展型非小细胞性肺癌,氩氦冷消融可有效地改善症状,促进肿瘤退缩,延长病人生存期,提高生存率。
出处 《中国交通医学杂志》 2006年第2期138-139,共2页 Chinese Medical JOurnal of Communications
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