母乳喂养新生儿低血糖影响因素观察

Influence Factors on the Incidence of Hypoglycemia in Breast-fed Newborns

目的:探讨纯母乳喂养新生儿血糖变化及低血糖的影响因素。方法:在出生后1、4、8、12、24、48、72h对纯母乳喂养的新生儿360例进行血糖系列监测。结果:新生儿出生后1h的平均血糖浓度较低为(2.8±0.95)mmol/L,4h后升高并逐渐稳定为(3.22±1.03)mmol/L;有糖代谢异常母亲的新生儿、巨大儿、低体重儿,其出生3d内低血糖的发生率分别为23.2%(16/69)、37.2%(35/94)、30.8%(12/39),显著高于无以上并发症的正常新生儿(13.3%,21/158)。结论:纯母乳喂养儿出生1h血糖偏低,有糖代谢异常母亲的新生儿、巨大儿、低体重儿,出生3d内低血糖发生率较高,应给予严密监测,以预防有症状的低血糖发生。

Objective： To study the influence factors on the incidence of hypoglycemia in breast-fed newborns. Methods： Blood glucose were measured in 306 breast-fed newborns at 1,4,8,12,24,48,72 hour after birth. Results： The incidence of hypoglycemia in the newborns whose mothers were complicated with diabetes or impaired glucose tolerance, in macro newborns （birth weight≥4000g） and in lower birthweight infants （birth weight〈2500g） were 23.2%（16/69）, 37.2 %（35/94） and 30.8% （12/39） respectively, which were much higher than that of normal newborns （ 13.3 %, 21/158）. Conclusion： In breast-fed newborns, monitoring of blood glucose should be given to those whose mothers were complicated with diabetes or impaired glucose tolerance, to macro-newborns and lower birth weight infants.