无精子症患者精浆果糖、α-糖苷酶及促卵泡激素水平研究

Researchon the level of fructose, alpha-glucosidase and FSH (follicle- stimulating hormone) in semen of non-obstructed azoospermia patient

目的:探讨精浆果糖、a-糖苷酶及促卵泡素(FSH)水平与无精子症的关系。方法:测定26例正常有生育能力男性(对照组)和66例无精子症患者(无精子症组)的精浆果糖含量、α-糖苷酶活性和FSH浓度,以此判断精囊、附睾功能及睾丸生精能力。结果:无精子症组精浆果糖含量平均为(2．817±1．683)g/L,对照组为(2．810± 1．463)g/L,2组差异无统计学意义(P>0．05)。无精子症组精浆α-糖苷酶活性为42．536±36．296,对照组为 75．744±61．421,2组差异有统计学意义(P<0,05)。无精子症组精浆FSH浓度为(16．400±2．727)mIU/ml,对照组为(4．900±1．181)mIU/ml,两组差异有统计学意义(P<0．05)。结论:检测精浆果糖含量、α-糖苷酶活性及 FSH浓度对无精子症的病因诊断有重要意义。

Objective： To investigate the relationship of the level of fructose, alpha- glucosidase and FSH （follicle-stimulating hormone） in semen with the non-obstructed azoospermia. Methods： To determine the concentration of fructose, alpha-glucosidase and FSH （follicle-stimulating hormone） in semen of 66 cases with non-obstructed nzoospermia and 26 cases of normal fertilize men. Results： The level of fructose in semen between the group of non-obstructed azoospermia [（2.817±1. 683） g/L] and the group of normal fertilize [（2.810±1. 463） g/L ] had no significant difference （P〉0.05）. The amount of alpha-glucosidase in group of non-obstructed azoospermia are （42. 536 ± 36. 296）. Compare to the group of normal fertilize （75. 744±61. 421）, There have statistical meaning. The concentration of FSH in the group of non-obstructed azoospermia are （16. 400±2. 727） mIU/ml, Compare to the group of normal fertilize [ （4. 900±1. 181）mIU/ml] . There have statistical meaning. Conclusions： The level of fructose, alpha-glucosidase and FSH （follicle-stimulating hormone） in semen have significant meaning on the pathogenesis of non-obstructed azoospermia.