卒中后抑郁障碍198例临床特点分析

Analyses of clinical features in 198 patients with post-stroke depression

目的探讨卒中后抑郁障碍的临床特点及其发生率。方法对198例入组患者采用抑郁自评量表进行评定分组,抑郁自评量表总分<30分为非抑郁组,≥30分为抑郁组。对抑郁组应用汉密尔顿抑郁量表进行抑郁程度评定,汉密尔顿抑郁量表总分<8分为无抑郁,≥8分为轻度抑郁,≥17分为中度抑郁,≥24分为重度抑郁,并对抑郁障碍的临床特点及其发生率进行分析。结果卒中后抑郁障碍发生率36.86%,其中轻度抑郁46例(63.01%),中度抑郁19例(26.03%),重度抑郁8例(10.96%)。卒中后抑郁障碍患者的主要临床特点为睡眠障碍、绝望、运动阻滞、焦虑等。结论卒中后抑郁障碍发生率较高,对患者的神经功能康复和日常生活有明显的负性影响。

Objective To explore clinical features and incidence of post-stroke depression （PSD）. Methods 198 stroke patients were assessed and divided with the Self-Rating Depression Scale（SDS） into non-depression（total score 〈 30） and depression（≥ 30） group. Severity of depression was assessed with the Hamilton Depression Rating Scale（HAMD） ： total score 〈8 was non-depression, ≥ 8 mild depression, ≥ 17 moderate and ≥ 24 grave. Results Incidence of post-stroke depression was 36. 86%, among them 46（63. 01%） were mild,19（26. 03%） moderate and 8（10. 96%） grave. The clinical features of PSD patients were sleep disorder, hopelessness, dyscinesia and anxiety and so on. Conclusion The incidence of post-stroke depression is higher and the PSD has significant negative effects on recovery of nervous function and daily life.