慢性阻塞性肺病并发抑郁障碍相关因素分析

Analyses of correlated factors of chronic obstructive pulmonary disease complicated by depression

目的探讨慢性阻塞性肺病患者并发抑郁障碍的相关因素。方法对162例慢性阻塞性肺病患者采用抑郁自评量表与自行设计的影响心理状态因素调查表进行抑郁状况和负性精神因素与抑郁障碍关系的调查。结果49.4%的慢性阻塞性肺病患者存在不同程度的抑郁障碍,其中轻度24.1%,中度16.7%,重度8.6%。慢性阻塞性肺病并发抑郁障碍者较未并发抑郁障碍者的病程长(P<0.01),动脉血氧分压和肺通气功能下降,动脉血二氧化碳分压升高(P<0.01);抑郁程度分别与生命安全感、无法根治、运动受限、影响家庭关系、经济负担重等因素呈正相关。结论生命安全感缺乏、无法根治、运动受限、影响家庭关系、经济负担重等因素是慢性阻塞性肺病患者易并发抑郁障碍的危险因素。

Objective To explore correlated factors of chronic obstructive pulmonary disease（COPD） complicated by depression. Methods Depressive status was assessed with the Self-rating Depression Scale （SDS） and relationship between negative mental factors and depression with the Self-made Inventory of Influencing Factors of Psycho-state in 162 COPD patients. Results 49.4% of the COPD patients have different degrees of depression, of them 24.1% was mild depression, 16.6% moderate and 8.6% grave. Course of the COPD complicated by depression was longer than that of the COPD without depression（P〈0.01）, and arterial partial pressure of oxygen and pulmonary ventilation function fell and arterial partial pressure of carbon dioxide rose（P〈0.01）. Depressive severity was positively related to deficiency of life safety, past recovery, movement disorder, influence of family relationship and economic burden, respectively. Conclusion Deficiency of life safety, past recovery, movement disorder, influence of family relationship and economic burden are risk factors of chronic obstructive pulmonary disease complicated by depression.