急诊冠脉介入疗法治疗急性心肌梗死近期疗效观察

Observation on Short Term Therapeutic Effects of Emergent Coronary Intervention in Treating Acute My-ocardial Infarction

目的:探讨急诊冠脉介入疗法(PCI)与静脉溶栓疗法早期开通梗死相关冠状动脉(IRA)后对QT离散度(QTd)的影响,为急性ST段抬高心肌梗死(STEMI)综合治疗措施的制订提供科学依据。方法:发病12h以内STEMI患者117例为入选对象,随机分为PCI组(56例)与静脉溶栓组(61例),重点考察治疗前、治疗24hQTd的变化。结果:治疗24h后2组QTd值均明显下降,但治疗后2组间比较具有显著性差异(P<0.01);PCI组与静脉溶栓组的IRA开通率分别为100%、73.8%(P<0.01),平均住院时间分别为14.8d、24.2d(P<0.01)。结论:急诊PCI宜作为治疗STEMI首选方案。

OBJECTIVE：To study the effect of percutaneous coronary intervention（PCI） and vein thrombolytic therapy on QT dispersion（QTd） after early recanalization of the infracted related artery（IRA） in order to provide the scientific reference for the comprehensive measures against acute ST-segment elevation after myocardial infarction（STEMI） .METHODS： 117 patients with STEMI were selected within 12 hours after the onset,and then randomly divided into PCI group（56 patients）and vein thrombolytic therapy group（61 patients） .QTd were determined before and 24h after treatment.RESULTS; The recanalization rates in PCI and vein thrombolytic therapy group were 100% and 73.8%, respectively（P〈 0.01） .The average days of hospitalization were 14.8 and 24.2d, respectively（P 〈0.01） .CONCLUSION; PCI is the optimal scheme for treatment of STEMI.