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瑞芬太尼在高血压患者胃镜检查中应用 被引量:1

Observation of efficacy and safety of sedation for gastroscopy with low dose of remifentanil in patients with hypertension.
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摘要 目的观察小剂量瑞芬太尼在高血压患者胃镜检查中的效果与安全性。方法需胃镜检查的高血压患者150例,随机分A(先表麻,再瑞芬太尼+丙泊酚静注)、B(先表麻,再瑞芬太尼+咪达唑仑静注)、C(仅表麻)三组,观察三组患者检查前、中、后血压、心率和脉搏血氧饱和度的变化及对检查感受的不适程度。结果A、B组对检查感受的不适程度均明显低与C组(均P<0.05),检查中A、B组流涎、恶心呕吐、躁动的发生率均显著低于C组(均P<0.05)。检查中A组收缩压、舒张压下降较B组明显。A组患者清醒时间为(1.6±1.4)分钟,B组患者即刻清醒。C组检查中收缩压、舒张压分别较检查前增高,心率增加。结论高血压患者胃镜检查中,应用小剂量瑞芬太尼加咪达唑仑或丙泊酚静注后均能使整个检查过程无痛苦反应,且安全性好。但小剂量瑞芬太尼加小剂量咪达唑仑避免了复合丙酚发生的低血压和意识模糊。 Objective The application of little dose remifentanil for gastroscopy in patients with hypertension. Methods One hundred and fifty patients were divided into three groups randomly. Patients' satisfaction during the procedure were compared with three groups. The changes of blood pressure, heart rate and pulse oxygen saturation were recorded and analysed. The recovery time of A,B group. Results The degree of discomfort in group A and B was remarkable lower as compared with C group. Conclusion With intravenous use of little dose of remifentanil in patients with hypertension, gastroscopy can be performed comfortablely and safely.
出处 《华中医学杂志》 2006年第2期99-100,共2页 Central China Medical Journal
关键词 胃镜检查 高血压病 瑞芬太尼 Gastroscopy Hypertension Remifentanil
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