地塞米松局部应用对悬雍垂腭咽成形术效果的影响

Injecting dexamethasone in oropharynx to reduce the postoperative syndrome of uvulopalatopharyngoplasty

目的探讨悬雍垂腭咽成形术（UPPP）中控制术后并发症的方法。方法治疗阻塞性睡眠呼吸暂停低通气综合征（OSAHS）23例，在手术开始之前或手术结束之后，在软腭双侧、悬雍垂、双侧腭咽弓各注射地塞米松稀释液1ml，地塞米松总用量5～10mg；对照组在术后使用地塞米松，每日10mg静脉滴注。观察两组患者手术后四种主要并发症的发生率。结果在咽部注射地塞米松的患者术后局部反应较轻，腭咽形态保持较好，疗效满意，各项指标均优于对照组。结论使用地塞米松局部注射的方法控制UPPP术后的咽部水肿，可有效地控制UPPP手术风险，减轻患者痛苦，提高UPPP的疗效。

Objective To introduce a method of reducing the postoperative syndrome of the uvulopalatopharyngoplasty（UPPP）. Method UPPP was performed for 23 patients with obstructive sleep apnea hypopnea syndrom operation（OSAHS）. Before or after the operation, dexamethasone was injected in oropharynx to control the edema of the oropharynx which caused by UPPP. Results Less syndrome had been occurred in these patients. Conclusion The edema of the oropharynx which caused by UPPP can be controlled by injecting dexamethasone in oropharynx. It can reduce the risk of the UPPP, and make the operation safer and more efficient.