2000年与2004年北京友谊医院手术患者抗生素应用情况调查分析

Analysis of Antibiotic Application in Surgical Patients in Beijing Friendship Hospital in 2000 and 2004

目的了解北京友谊医院手术患者抗生素的使用现状和存在问题,为临床安全、合理、有效地使用抗生素提供参考。方法随机抽取2000年和2004年手术患者的住院病历各178例、172例,对抗生素应用情况进行回顾性调查。结果2000年和2004年手术患者抗生素使用率均为100%,合理使用率分别为65.7%和46.5%。其中,单纯预防性用药者分别占43.8%和43.6%,预防合并治疗性用药者分别占56.2%和56.4%。经验性用药分别占100%和98.3%。单联、二联、三联、四联及四联以上使用抗生素者2000年和2004年分别占56.5%和44.4%,36.6%和50.0%,6.9%和4.4%,0和1.1%。结论手术患者抗生素的使用存在不合理现象,应引起临床医师的重视。

Objective This study was performed to investigate the status and exiting problem of antibiotic use in surgical patients in Beijing Friendship Hospital and provide reference for safe,rational and effective in antibiotic use clinic. Methods The data of surgical patients（n= 178） in 2000 and surgical patients（n= 172） in 2004 were collected randomly and analyzed retrospectively. Results Of the selected patients in 2000 and 2004,100 % were receiving antibiotics. The rate of rational antibiotic use was 65.7% and 46. 50% respectively. The purpose of antibiotic use was for simple prophylaxis in 43. 8% and 43. 6%, for both treatment and prophylaxis in 56. 2% and 56. 4% respectively. The empiric use of antinations composed 100% and 98. 3% respectively. In 56.5% and 44.4%, 36.6% and 50.0%, 6.9% and 4.4%, 0 and 1.1% of the users, a single, two, three and four or more agents were used in combinations, respectively. Conclusion There is unrational antibiotic usage in clinical practice in our hospital,and the clinicians should pay attention to it.