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不稳定型心绞痛合并糖耐量低减患者的血脂与PAI-1的特点 被引量:1

Status of bloodlipid and PAI-1 in the patient with unstable angina accomplied by IGT
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摘要 目的通过测定纤溶酶原激活物抑制剂-1(PAI-1)及纤溶酶原激活物(t-PA)活性,探讨不稳定型心绞痛(UAP)合并糖耐量低减(IGT)患者的低纤溶活性状态及其特点。方法把UAP患者分为糖耐量正常组和IGT组,测PAI-1t、-PA含量及血脂、胰岛素水平。结果UAP合并IGT患者较正常对照组PAI-1增高,t-PA下降,t-PA/PAI-1比值下降(P<0.01),总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、三酰甘油(TG)增高,高密度脂蛋白胆固酶(HDL-C)降低(P<0.05)。较UAP不合并IGT患者PAI-1增高,t-PA下降,t-PA/PAI-1比值下降(P<0.05)。结论UAP合并IGT患者存在较低的纤溶活性。
作者 王丽 胡健
出处 《中国心血管杂志》 2006年第2期135-137,共3页 Chinese Journal of Cardiovascular Medicine
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