高氟饮水与儿童血铅水平关系的流行病学研究

Epidemiological investigation about the relation between blood lead level and high-fluorine drinking water in children

目的：了解高氟饮水对0-8岁儿童血铅水平的影响及特点。方法：采用分层整群随机抽样的方法，对饮用不同含氟量水质的1983例0-8岁儿童进行了血铅水平测定，并对可能影响儿童血铅水平的相关因素进行了流行病学调查分析。结果：调查儿童血铅范围在14．4-223．8μg／L之间，高氟饮水儿童血铅水平均数为93．0μg／L，饮用正常水质儿童血铅水平均数为80．4μg／L，两组差异显著；按照饮用水含氟量高低比较儿童血铅均数水平呈由高氟水到轻高氟水逐渐降低趋势。多元逐步回归分析亦显示饮用高氟水与血铅值相关。结论：高氟饮水是影响儿童血铅水平重要危险因素。

Objective： To understand the effect of high -fluorine drinking water on blood lead level among children aged 0 - 8 years and its characteristics. Methods： Blood lead levels by stratified - clustered - random sampling and simple random sampling method a- mong 1 983 children aged 0-8 years were detected to investigate and analyze factorz related to children＇s blood lead level. Results： The scopes of children＇s blood lead was 14. 4 - 223. 8 μg/L. The average blood lead of children who drink high - fluorine drinking water was 93.0μg/L, and the average blood lead of children who drink normal water was 80. 4μL with obvious differences. The children＇s blood lead level had decending trend from high to low fluorine content in drinking water. Multiplex and gradual return analysis showed that there were relations between drinking high- fluorine drinking water and blood lead value. Conclusion： High- fluorine drinking water is the important and dangerous factor related to children＇s blood lead level.