Ⅱ_(B)、Ⅲ_(B)期宫颈癌的血管性介入治疗(附71例分析)

Effect of intra-arterial infusion chemotherapy or chemoembolization in patients with stage Ⅱ_B or Ⅲ_B uterine cervical cancer

目的评价宫颈癌血管性介入治疗在同步放化疗中的价值。方法将41例ⅡB期、30例ⅢB期宫颈癌患者随机分为动脉化疗组和化疗栓塞组进行治疗观察。结果临床缓解率达100%。ⅡB期宫颈癌患者的5年总生存率为73.2%,ⅢB期为60%。化疗栓塞组生存率高于单纯化疗组,但无统计学差异(P>0.05)。结论宫颈癌血管性介入治疗起效快,疗效好,是同步放化疗的一项重要内容。

Objective To evaluate the clinical efficacy of intra-arterial infusion chemotherapy or chemoembolization in patients with stage ⅡB or ⅢB uterine cervical cancer treated with concurrent radical radiotherapy. Methods A total of 71 patients with cervical cancer （41 of stage ⅡB,and 30 ⅢB） were randomly divided into intra-arterial infusion chemotherapy group and chemoembolization group. Results The overall response rate was 100 percent. Five-year overall survival rate was 73. 2 percent in patients with stage ⅡB cervical cancer and 60 percent with stage ⅢB. Five-year overall survival rate of chemoembolization group was higher than infusion chemotherapy group, but there was no statistical difference between the two groups （P〉0. 05）. Conclusion Intra-arterial infusion chemotherapy or chemoembolization has great efficacy.