钙非依赖型磷脂酶A_2活性的调节及生物学功能
被引量:1
摘要
钙非依赖型磷脂酶A2(iPLA2)属于Ⅵ型磷脂酶A2,其活性受蛋白激酶C(PKC)、钙调蛋白、活性氧等物质的调节。iPLA2分解产生的花生四烯酸(AA)和溶血磷脂是一类信号传递因子,参与调节多种细胞功能。该文就iPLA2的调节及生物学功能作一综述。
出处
《国际检验医学杂志》
CAS
2006年第4期373-375,共3页
International Journal of Laboratory Medicine
参考文献13
-
1Dennis EA.Diversity of group types,regulation,and function of phospholipase A2.J Biol Chem,1994,269(18):13057-13060.
-
2Winstead MV,Balsinde J,Dennis EA.Calcium-independent phospholipase A(2):structure and function.Biochim Biophys Acta,2000,1488(1-2):28-39.
-
3Nofer JR,Junker R,Walter M,et al.Phospholipase A(2) is involved in thapsigargin-induced sodium influx in human lymphocytes.Arch Biochem Biophys,2000,374(2):213-221.
-
4Akiba S,Ohno S,Chiba M,et al.Protein kinase Calpha-dependent increase in Ca2+-independent phospholipase A2 in membranes and arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells.Biochem Pharmacol,2002,63(11):1969-1977.
-
5Birbes H,Gothie E,Pageaux JF,et al.Hydrogen peroxide activation of Ca(2+)-independent phospholipase A(2) in uterine stromal cells.Biochem Biophys Res Commun,2000,276(2):613-618.
-
6Martinez J,Moreno JJ.Role of Ca2+-independent phospholipase A2 on arachidonic acid release induced by reactive oxygen species.Arch Biochem Biophys,2001,392(2):257-262.
-
7Yellaturu CR,Rao GN.A requirement for calcium-independent phospholipase A2 in thrombin-induced arachidonic acid release and growth in vascular smooth muscle cells.J Biol Chem,2003,278(44):43831-43837.
-
8Murakami M,Kambe T,Shimbara S,et al.Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways.J Biol Chem,1999,274(5):3103-3115.
-
9Balsinde J,Balboa MA,Dennis EA.Antisense inhibition of group VI Ca2+-independent phospholipase A2 blocks phospholipid fatty acid remodeling in murine P388D1 macrophages.J Biol Chem,1997,272(46):29317-29321.
-
10Baburina I,Jackowski S.Cellular responses to excess phospholipid.J Biol Chem,1999,274(14):9400-9408.
同被引文献9
-
1张静,瞿介明,潘珏,何礼贤,欧周罗,张杏怡,陈雪华.内毒素耐受大鼠与正常大鼠急性肺损伤反应比较[J].中国呼吸与危重监护杂志,2003,2(6):346-350. 被引量:11
-
2陈思锋,吴中立.体液和组织磷脂酶A_2简便快速测定法[J].第二军医大学学报,1989,10(3):254-256. 被引量:210
-
3王凤君,赵云,谢尔凡,尤忠义.高效液相色谱法测定生物样品中磷脂含量[J].第三军医大学学报,1996,18(1):67-68. 被引量:18
-
4中华医学会呼吸病学分会.急性肺损伤/急性呼吸窘迫综合征的诊断标准(草案)[J].中华结核和呼吸杂志,2000,23(4):203-203.
-
5CALLOL L, BARBERO E A, BLASCO R, et al. New method of collection of bronch - alveolar lavage in rat [ J ]. Respir Med, 1994, 88:399.
-
6SCHMID RA, YAMASHITAL M. Effect of pentoxifylline in a canine and porcine model of pulmonary allograft reperfusion injury [ J ]. J Heart Lung Transplant, 1997,16:366.
-
7WIEDEMANN HP, ARROLIGA AC, KOMARA JJ JR. Emerging systemic pharmacologic approaches in acute respiratory distress syndrome[ J]. Respir Care Clin N Am,2003 ;9:419.
-
8HADDAD JJ, SAFIEH - GARABEDIAN B, SAADE NE, et al. The biphasic immunoregulation of pyrimidyl-piperazine (Y- 40138) is IL-10 sensitive and requires NF-kappa B targeting in the alveolar epithelium[ J ]. Br J Pharmacol,2001,133 :49.
-
9KRAKAUER T. Pentoxifylline inhibits ICAM-I expression and chemokine production induced by preinflammatory cytokines in human pulmonary epithelial cells [ J ]. Immunopharmacology, 2000,46 : 253.
-
1万星,石刚刚.钙非依赖磷脂酶A_2参与非L型钙通道开放引起的心肌细胞缺氧复氧损伤[J].汕头大学医学院学报,2013,26(4):206-208. 被引量:2
-
2吴国球,高茂馗,钱娟英,王喜红.通过维生素D_(3)结合蛋白介导的溶血磷脂对人外周巨噬细胞的激活作用[J].南京铁道医学院学报,1999,18(3):176-178.
-
3邓艳春.糖尿病患者的心理问题及护理对策[J].中国实用医药,2009,4(3):222-223. 被引量:1
-
4颜光涛,郝秀华,辛宏,王录焕,李英丽.磷脂酶A_2活性对中性粒细胞凋亡的影响[J].中国应用生理学杂志,1999,15(4):293-293.
-
5张斌,李红梅,王媛,王发强,王一阳,吕秀秀,戚仁斌,陆大祥,王华东.芍药苷减轻小鼠LPS性急性肺损伤的作用机制研究[J].中国病理生理杂志,2011,27(10):1956-1960. 被引量:16
-
6陈莲,高洪,赵汝,高利波.喹乙醇对鸡生物膜磷脂酶A_2活性和膜磷脂代谢的影响[J].中国病理生理杂志,2007,23(8):1627-1630. 被引量:2
-
7廖璞,廖雪松,王淑琴,唐唯,康格非.磷脂酶A_2活性对高糖或(和)高胰岛素环境下培养的大鼠血管平滑肌细胞增殖的影响[J].疾病控制杂志,2000,4(3):202-204.
-
8管成康,管帅.单增李斯特菌与细胞自噬[J].科技与创新,2016(22):24-25.
-
9母敬郁,吕晓红,康劲松,丁克祥,杨翰仪.大鼠缺血及再灌注过程中脑组织磷脂酶A_2作用的实验研究[J].中国老年学杂志,1996,16(2):97-98. 被引量:1
-
10颜光涛,郝秀华,田亚平,李振甲.磷脂酶A_2活性对大鼠多形核白细胞化学发光的影响[J].上海免疫学杂志,1995,15(5):309-311. 被引量:1