妊高征患者血清尿素氮、肌酐和尿酸水平的变化

Changes of the levels of serum nitrogen,creatinine,and uric acid in pregnancy-induced hypertension syndrome

目的通过测定妊娠高血压综合征孕妇血清尿素氮、肌酐和尿酸水平,探讨其临床意义。方法采用生化分析仪测定50例妊娠高血压综合征孕妇(实验组)与43例正常妊娠的孕妇(对照组)血清尿素氮、肌酐和尿酸水平。结果实验组血清尿素氮、肌酐浓度均高于对照组(P<0.01);血清中尿酸水平也显著增高(P<0.005),血清尿素氮、肌酐、尿酸水平随着病情加重,均有升高趋势(P<0.01)。结论测定妊娠高血压综合征孕妇血清尿素氮、肌酐和尿酸对了解病情严重程度有一定的临床意义。

Objective To explore the clinical value of serum nitrogen, creatinine, and uric acid in women with pregnancy-induced hypertension syndrome （PIH）. Methods The levels of serum nitrogen, creatinine, and uric acid in 50 PIH patients （ PIH group） and 43 normal pregnant women （ control group） were determined and compared. Results The serum levels of nitrogen and creatinine （ P 〈 0.01 ） , and uric acid （ P 〈 0.005 ） in PIH group were significant higher than those in control group. The levels of serum nitrogen, creatinine, and uric acid were related with the severity of PIH. Conclusion The serum levels of nitrogen, creatinine, and uric acid may predict the severity of PIH.