胆汁反流性胃炎与幽门螺杆菌的关系

Relationship between bile reflux gastritis and Helicobacter pylori

目的探讨幽门螺杆菌(Hp)感染与胆汁反流性胃炎的关系。方法采用病理组织学检查和快速尿素酶试验对胃镜和病理组织学诊断明确的104例胆汁反流性胃炎及148例慢性胃炎的患者行Hp检测,比较两组患者Hp检出阳性率。结果胆汁反流性胃炎组Hp阳性率为22.1%,慢性胃炎组Hp阳性率为43.9%。两组比较差异有显著性意义(P<0.01)。结论胆汁反流性胃炎的患者,反流的胆汁可能有抑制和杀灭Hp的作用。

Objective To investigate the relationship between Helicobacter pylori and bile reflux gastritis. Methods 104 patients with bile reflux gastritis and 148 patients with chronic gastritis were given Helicobacter pylori detection by both histology （ Giemsa stainingl and rapid urease test （RUT）. Results Helicobacter pylori-positive rates were 22. 1% in bile reflux gastritis group and 43. 9% in chronic gastritis group, with significant difference between the two groups （P 〈 0.01 ）. Conclusion Refluxed bile may have the function of inhibiting and killing Helicobacter pylori in patients with bile reflux gastritis.