肿瘤患者医院感染相关因素的调查

Nosocomial Infection and Related Factors in Cancer Patients: A Clinical Analysis

目的了解肿瘤患者医院感染发病情况，以制定有效的防控措施。方法回顾性调查2000-2004年住院病历25005份，逐份进行查阅分析。结果5年出院25005例，发生医院感染1238例（1376例次），感染率为5．0％（5．5％），各感染部位以呼吸道为最高46．8％，医院感染与年龄、住院时间、原发肿瘤疾病、死亡率等有关，化疗科医院感染率最高7．9％，明显高于外科、放疗科；真菌感染率呈逐年上升趋势。结论必须持续改进、落实医院感染的监控措施，特别是化疗、放疗、呼吸道感染和真菌感染患者的重点监测和管理。

OBJECTIVE To evaluate the nosocomial infection and related factors in hospitalized cancer patients so as to enhance the monitoring and controlling of the incidence rate of nosocomial infection in cancer hospital. METHODS From 2000 to 2004,25 005 hospitalized cases were reviewed and included for retrospective analysis in this study. RESULTS The nosocomial infection rate in this cohort was 5.0% （1 238/25 005） with a highest incidence of 46.8% in the respiratory system. Statistic analysis indicated the nosocomial infection was highly related to hospitalized period, age, primary tumor disease and mortality. The incidence of nosocomial infection in the department of chemotherapy was the highest（7. 9%）, which was higher than that in departments of surgery （3.2 % ） and radiotherapy（4.9 % ）. The incidence of fungal infection was an increasing tendency as compared with the results from 2000 to 2004. CONCLUSIONS The continuous quality improvement must be executed on nosocomial infection of monitor and control. It is important to monitor nosocomial infection in patients with chemotherapy and with radiotherapy,or with respiratory tract infection or fungal infection in cancer hospital.