临床常见革兰阴性菌的分布动向及耐药趋势

The Distribution and Drug Resistance of the Common Clinical Gram-Negative Bacillus

监测革兰阴性菌的分布动向及耐药趋势,为临床合理使用抗菌药物提供依据。3年间临床分离致病菌以革兰阴性杆菌为主,革兰阴性杆菌检出率逐年下降,非发酵革兰阴性杆菌的比例逐年上升;加酶抑制剂的抗菌药物较不加酶抑制剂的抗菌药物对非发酵革兰阴性杆菌显示了不同程度的抑菌优势,肠杆菌科革兰阴性杆菌ESBLS检出率逐年增加。

To determine the distribution and drug resistance tendency of Gram-negative bacillus so as to provide a reasonable selection for antibiotic in clinical treatment. The clinical isolates bacillus were mainly Gram-Negative bacillus during three years. The detection out ratio for Gram-Negative bacillus had decreased gradually but the ratio for non-fermental gram-negative bacillus had increased. The combinations of antibiotic and enzyme inhibitor has more antibacterial activity to non-fermcntal gram-negative bacillus than antibiotic. The detection out ratio for ESBLs had gradually increased.