降酶口服液对慢性乙型肝炎的治疗作用

Therapeutic effect Jiangmei drink on chrnic hepatitis B

目的:观察降酶口服液对慢性乙型肝炎的治疗作用,并探究其作用机制。方法:慢性乙型肝炎264例,随机分为两组,治疗组(184例)和对照组(80例)患者分别给予降酶口服液和护肝胶囊治疗2个月,观察治疗前后两组患者的肝功能(ALT、AST、TBil、PT、A/G)及肝脏病理组织学改变。结果:临床总有效率治疗组为89·1%,对照组为78·8%,两组比较差异有显著性意义(P<0·05)。治疗后治疗组患者肝功能明显改善,19例患者行肝活检证实肝脏炎症活动度明显减轻,肝纤维化也有一定程度改善。结论:降酶口服液对慢性乙型肝炎有较好的临床疗效。

Objective： To observe the therapeutic effect of Jiangrnei Drink on chronic hepatitis B. Methods： Two hundred and sixty lout cases of chronic hepatitis B were randomly divided into 2 groups. The treatmen group （ 184 cases） and the con- trol group （80 cases） were, respectively, given Jiangmei drink and Hugan capsules for 2 months. Then their liver functions （ALT, AST, TBil, PT, A/G） before and after the treatment and the pathogenic histological changes in the liver were observed. Results： The total effective rate in the treatment group was 89.1% while 78.8% in the control group. There was significant difference between them （P〈 0.05） ; After treatment, the liver function of the treatment group was improved remarkably, In 19 cases, the biopsy of liver tissue showed that the activity of the inflammation was relieved, The liver fibrosis was also improved to a certain degree, It can also protect the liver from fat degeneration and necrosis, Conclusion： Jiangmei drink has protective function on patients with chronic hepatitis B.