妊高征早期肾损害相关因素分析

The Correlative Factors of Kidney Injury in Early of Hypertensive Disorder Complicating Pregnancy

目的:分析妊高征患者早期肾损害的相关因素。方法:选择妊高征患者85例,正常妊娠60例,其中妊高征患者分为轻、中、重3组,分别记录(MAP),检测尿NAG、2β-MGI、gG等,并进行统计学分析。结果:妊高征患者的轻重程度与MAP、尿NAG、2β-MGI、gG等因素有关而与孕周无相关。结论:妊高征患者不仅有肾小球滤过率降低,同时伴有肾小管功能受损,为妊高征患者早期肾损害提供依据。

Objective： To explore the correlative factors in the patients of hypertensive disorder complicating pregnancy（HDCP） with early renal injury;Methods： 85 patients with HDCP and 60 normal pregnancies were enrolled in this study. 85 patients with HDCP were divided into three groups： minor group, moderate group, and serious group. The level of MAP、urine NAG、β2--MG, IgG were measured. The data was managed with statistics. Results： There was a significant correlative effect between the surveillance of the patients with HDCP and level of MAP、 urine NAG、 β2--MG and IgG but the weeks of pregnancy. Conclusions： The patients with HDCP not only have the declining of glomerular filtration rate but also have the injury of renal tubule in early of HDCP.