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胃癌血清和尿液中血管内皮生长因子测定及意义 被引量:3

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摘要 目的测定胃癌患者血清和尿液中血管内皮生长因子(VEGF)水平,探讨VEGF与胃癌关系及意义。方法应用酶联免疫吸附法对34例胃癌患者术前、术后血清及尿液中VEGF测定并对照分析。结果胃癌组术前血清、尿液VEGF水平明显高于正常组。尿液VEGF水平与肿瘤分化程度、侵袭程度、有无淋巴结转移等密切相关。且术前尿液组的VEGF水平明显高于术前血清组(P<0.01)结论VEGF与胃癌发生、发展、转移密切相关。尿液VEGF含量增强,预示胃癌的转移和预后不良。
出处 《中国综合临床》 北大核心 2006年第5期391-392,共2页 Clinical Medicine of China
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