平阳霉素与培普利欧对舌癌细胞集落增殖的抑制作用比较

THE ANTITUMOR EFFECT OF PYM AND PEPLOMYCIN ON TCA LINE WITH COLONY INHIBITION TEST OF TUMOR

本文采用细胞集落技术，比较了平阳霉素和培普利欧对舌癌细胞增殖的影响。结果表明两药在相同条件下，对舌癌细胞的增殖抑制作用分别是９４．８７、９４．２３（０．６μｇ／ｍｌ）；９２．３１，８３．９８（０．２μｇ／ｍｌ）；５１．９２、６４．７５（０．０５μｇ／ｍｌ）。经统计学分析两组间无显著性差异，提示两药体外对舌癌细胞的增殖影响无差异。

edical University Shanghai(200011)Using colony technique to compare PYM and peplomycin aganist Tca line ,the re-sult showed that the rate of inhibition was 94.87,94.23;92.31.83.98;51.92, 64.75 when the drug concentrat ion was 06μg/ml,0.2μg/ml and 0.05μg/ml resp-ectively. The statistics was not significantly between two groups,indicating that peplomycin effected on Tca line in vitro was similar to PYM