血清微量元素和幽门螺杆菌与胃癌关系的研究

Study on Relationship Between Serum Trace Element and Helicobacter Pylori with Gastric Carcinoma

目的:探讨胃癌患者体内微量元素变化和幽门螺杆菌感染的关系。方法:采用抗幽门螺杆菌抗体的测定和14C-尿素呼气试验对胃癌患者、消化性溃疡患者、慢性胃炎和正常对照组进行幽门螺杆菌感染测定,同时进行血清M g、C a、F e、Cu、Zn、Se 6种微量元素的测定。结果:胃癌组M g、C a、Cu、Zn明显低于对照组,胃癌组年龄高于其余各组。胃癌组Hp感染率为64.3%(18/28),溃疡组为87.5%(14/16),慢性胃炎组20%(2/10),对照组36.4%(4/11)。结论:胃癌的发生与Hp感染有密切关系。胃癌患者血清M g、C a、Cu、F e存在明显的改变。

ObjectivezStudy on relationship between the change of serum trace element and helicobacter pylori inL fection in patients with gastric carcinoma. Methods ： At the same time determination of Mg 、 Ca 、 Fe、 Cu 、Zn、Se 6 serum trace elements, anti Hp-IgG and ^14C-urea breath test were conducted on gastric carcinoma, digest ulcerating, chronic stomach inflammation and normal control. Result：The serum level of Mg,Ca,Cu, Zn in patient with gastric carcinoma was obviously lower than that in normal control ,the cancer group age was older than the other groups. The infection rates of Hp in stomach cancer,ulcers chronic stomachitis and control group were 64.3%（18/28）,87.5%（14/16）,20% （2/10） and 36.4% （4/11）. Conclusion;The obvious change of serum Mg,Ca,Cu ,Zn occurs in patient with gastric carcinoma. The occurrence of gastric carcinoma has close relationship with Hp.