摘要
将滥用海洛因者分成滥用2a以下及滥用2a以上二组,通过心导纳图法测定左心功能,结果显示:滥用早期左心室舒张功能改变明显,冠脉灌注压明显下降,收缩功能影响较少;滥用时间越长,左心室收缩功能损害严重,外周血管阻力越大,上述结果对于指导临床合理用药,提供了理论依据。
heroin addicts were divided into two groups according to theirheroin abusing time, Group One: abusing heroin less than two years, Group Two: morethan two years. Their function of left ventricle was determined by electrical admitlanceplethysmogram. The results showed that the diastolic function of left ventricle changedapparently and the coronary blood pressure dropped significantly in Group One; thesystolic function of left ventricle was greatly damaged and total periphery blood vesselresistance increased in Group Two which suggested that heroin abuse had adverse effect on the function of left ventricle.