免疫化学粪便隐血检查与结肠疾病(附107例报道)

RELATIONSHIP BETWEEN IMMUNOLOGICAL DETECTION OF FECAL OCCULT BLOOD AND COLORECTAL DISEASE

对107例有腹部症状病因待查患者采用免疫化学粪便隐血试验（OC-HEMODIA法）与联苯胺隐血试验进行了同步检查对比，并以结肠镜、病理活检结果为根据观察了OC-HEMODIA阳性与结肠疾病间的关系。结果显示：OC－HEMODIA阳性率（34．58％）显著高于联苯胺法（16．82％），两者比较P＜0．01；结肠癌患者OC－HEMODIA阳性率93．75％，联苯胺法50％，P＜0．025；结肠息肉与结肠炎患者两种隐血试验阳性率均低；镜检正常者两种隐血检查结果均为阴性。文中分别讨论了OC-HEMODIA法的敏感性、特异性、选择性特点，其阳性与结肠癌、结肠息肉及其他疾病间的关系。

With immunochenlical fecal occult blood test (OC-Hemodia) and Hemoccult Ⅱ, we observed, 107 cases with abdominal symptoms whose causes were unknown. By colic endoscope and histopathology, the relationship between colorectal diseases and positive OC-Hemodia were analysed. The results showed OC-Hemodia positive rate (34.58%) was significantly higher than Hemoccult Ⅱ(16.82%) (P<0.01); For colorectal carcinoma patients the positive incidence of OC-Hemoidia was 93.75%, Hemoccult Ⅱ 5% (P<0. 025); When fecal occult blood tests detected colicpolyps and chronic colitis, the positive rates were low; while for nomal colon cases,both tests were negative. These data indicate the high sensitivity、specificity and selectivity of OC-Hemodia in detecting colorectal diseases.