糖尿病视网膜病变发病机制的研究进展

The pathologic mechanism of diabetic retinopathy

糖尿病视网膜病变是糖尿病的重要并发症之一,它与高血糖、多元醇代谢异常、蛋白质非酶糖化、细胞凋亡、DG2PKC系统的激活、细胞因子及自由基作用等多种因素有关。本研究就其病理、发病机制作一综述。

Diabetic retinopathy is one of the severe complications of diabetes, it is related to various factors, such as hyperglycemia abnormal metabolism of polyethanol, nonenzymatic glycation, apoptosis, activated DG2, PKC system, cell growth factor and free radical. This paper summarized its pabhologic mechanism.