主动脉、桡动脉和内乳动脉粥样硬化与微生物感染的关系

The Relationship between Infection of Microorganism and Atheromatous Sclerosis of Aorta, Radial Artery and Internal Mammary Artery

目的:探讨人主动脉、桡动脉和内乳动脉粥样硬化与微生物感染的关系。方法:搭桥手术中成功取得主动脉碎片(全层)30例、桡动脉30例和内乳动脉20例,组织行PCR检测及病理学分析,评估血管病变程度并分级。结果:30例主动脉、30例桡动脉、20例内乳动脉其轻度病变组与重度病变组肺炎衣原体(CPn)、幽门螺旋杆菌(HP)、巨细胞病毒(CMV)的PCR检测阳性率比较,差异均无统计学意义(P>0.05)。结论:CPn、HP、CMV感染与动脉硬化有关,但与主动脉、桡动脉、内乳动脉的动脉病理改变程度无关。

Objective： To investigate the relationship between infection of microorganism and atheromatous sclerosis of aorta, radial artery and internal mammary artery. Methods： The aorta fragment full thickness （thirty cases）, radial artery（thirty cases） and internal mammary artery （twenty cases） were obtained in CABG, the tissue was measured by PCR and pathological analysis and the degree of pathological changes was evaluated and classified. Results： The positive rates of C pneumoniae （CPn）, H.Pylori （Hp） and Cytomegalovirus （CMV） measured by PCR that were in the mild pathological change group and the severe pathological change group of aorta （thirty cases）, radial artery （thirty cases） and internal mammary artery （twenty cases） were not significantly different （P 〉 0.05）. Conclusion： The infection of C pneumoniae, H.Pylori and Cytomegalovirus are related to arteriosclerosis, but not related to the degree of pathological changes in aorta, radial artery, internal mammary artery.