5Fu L, Cheng Y C. Role of additional mutations outsidethe YMDD motif of hepatitis B virus polymerase in L(-)SddC (3TC) resistance [ J] . Biochem Pharmacol,1998(55) :1567.
6Lai C L,Chien R N , Leung N W Y , et al. A one-yeartrial of lamivudine for chronic hepatitis B [ J]. N Engl JMed, 1998,339(24) :61.
7秦大莲,陈美娟,肖顺汉,等.药理学实验指导[M].泸州:泸州医学院药理学教研室,2006:63.
8Pugh J C , Yaginuma K, Koike K, et al. Duck hepatitisB virus ( DHBV ) particles produced by transientexpression of DHBV DNA in a human hepatoma cell lineare infectious in vitro [ J]. J Virol, 1988,62(9):3513.
9Sakurai N,Nagai,M.Chemical constituents of original plants of Cimicifugae Rhizoma in C hinese medicine[J].Yakugaku Zasshi,1996,116(11):850-865.
10Yoshihiro Mimaki,Isao Nadaoka,Masaaki Yasue,et al.Neocimicigenosides A and B,Cycloartane Glycosides from the Rhizomes of Cimicifuga racemosa and their effects on CRF-stimulatef ACTH secretion from At T-20 cells[J].Journal of Natural Products,2006(69):829-832.