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第四代孕激素研究进展 被引量:16

Advance in Fourth Progestin
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摘要 目的介绍第四代孕激素的药理学特性和临床应用状况。方法以国外近年研究结果为依据,总结第四代孕激素的药理作用特点。结果第四代孕激素与孕酮受体的结合更具选择性,与其他甾体激素受体几乎不结合。不抵消雌激素对血管的保护作用。无雄激素、雌激素或糖皮质激素活性,不影响脂代谢,作用更接近于天然孕酮。结论第四代孕激素更适合应用于激素补充疗法。
出处 《中国药学杂志》 CAS CSCD 北大核心 2006年第8期572-576,共5页 Chinese Pharmaceutical Journal
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