氯诺昔康超前镇痛在阴式子宫切除术中的应用

Application of Preemptive Lornoxicam in the Patients Undergoing Vaginal Hysterectomy

目的：探讨氯诺昔康超前镇痛用于阴式子宫切除术患者的安全性和有效性。方法：40例ASA Ⅰ-Ⅱ级择期行阴式子宫切除术惑者，随机分为观察组和对照组。观察组于切皮前静脉给予氯诺昔康16mg作为超前镇痛，观察组则静脉给予生理盐水4ml。分别于术后4，8，12，24小时观察并记录两组病人杜冷丁使用情况和不良反应，以视觉模拟评分（VAS）评价其镇痛效果，以舒适评分标准（BCS）判定病人满意程度。结果：在术后各时点，观察组杜冷丁使用倒教和VAS评分明显低于对照组。BCS评分显著高于对照组（P（0．05），两组病人术后不良反应无显著性差异（P〉0．05）。结论：氯诺昔康超前镇痛用于阴式子宫切除术患者，可明显减少术后疼痛，病人满意程度高，不良反应少，安全可靠。

Objectives：To evaluate the effects and safety of preemptive analgesia of lornoxlcam in the patients undergoing the vaginal hysterectomy. Methods：We randomly divided 40 patients with ASA I - H scheduled for the vaginal hysterectomy into the study group and the control group. The patients in the study group were administrated with 16rag lomoxicam intravenously before skin incision, while the patients in the control group were administrated with 4ml 0.9% NS. The side effects and the use of pethidine at 4, 8, 12, 24 hours after the operation were recorded. The analgetic effect was measured with VAS and the satisfactory degree of the patients was evaluated with BCS. Results： The number of patients using pethidine and the scale of VAS in the study group were lower than those in the control group at 4, 8,12, 24 hours after the operation（ P 〈 0.05）, while the scale of BCS was higher（ P 〈 0.05）. There was not significant difference for the side effect between the two groups （ P 〉 0.05 ）. Coneausions： The preemptive analgesia of lomoxieam in the patients undergoing the vaginal hysterectomy could produce favorably analgetic effect and the patients were satisfied. The side effects were few, and it was safe and reliable.