Influence of HBcAg in liver cell plasma on expression of transforming growth factor-beta 1 in liver tissue of low-grade chronic hepatitis B patients

AIM： To study the influence of HBcAg on the expression of transforming growth factor-beta 1 （TGF-131） in liver tissue of low-grade chronic hepatitis B （CHB） patients. METHODS： The expression of T（3F-β1 and HBcAg in liver samples from 93 low-grade CHB patients was detected by immunohistochemistry and valuated by semi-quantitative scoring. RESULTS： In the 93 low-grade CHB patients, HBcAg was expressed in cell plasma but not in the liver tissue. There was no significant difference between the two groups. CONCLUSION： The expression of TGF-β1 is not related with HBcAg expressed as plasma type in the tissues of low-grade CHB patients.

瞄准：在转变生长因素贝它的表示上学习 HBcAg 的影响 1 (TGF-beta1 ) 在低档的肝织物长期的肝炎 B (CHB ) 病人。方法：在从 93 个低档 CHB 病人的肝样品的 TGF-beta1 和 HBcAg 的表示被半量的得分被免疫组织化学和 valuated 检测。结果：在 93 个低档 CHB 病人， HBcAg 在房间血浆然而并非在肝织物被表示。在二个组之间没有有效差量。结论：TGF-beta1 的表示没被联系，当血浆录入低档 CHB 病人的纸巾， HBcAg 表示了。