肺癌患者手术前后肿瘤标志物的检测及其临床意义

The Change of tumor markers in lung cancer patients before and after surgery

目的探讨肺癌肿瘤标记物手术前后变化及其临床意义。方法选经手术治疗26例肺癌患者,监测术前和术后第8天的肿瘤标记物CA50、CEA、AFP、SF、β2-MG的变化。结果术后CA50、SF、β2-MG和CEA水平较术前减低,而AFP手术前后变化不大。结论通过监测肿瘤标记物CEA、β2-MG、CA50水平改变可以协助肺癌手术疗效的判断,具有简便、经济的特点,在临床中具有一定的价值。

Objective： To investigate the change and significance of tumor markers in patients with lung cancer before and after surgery. Methods：The tumor markers CA50,CEA,AFP,SF andβ2- MG of 26 patients with lung cancer were tested pre and post operatively. Results：The levels of CA50,CEA,AFP,SF and β2 - MG after surgery were significantly lower than that of before surgery, except AFP. Conclusion： Monitor of the changes of CA50, CEA, SF and β2 - MG could be helpful to evaluate the effects of surgery.