应激肽在高原病康复治疗中的应用

Application of the hypoxia stress peptide in the high altitude disease rehabilitative treatment

目的探讨应激肽在筛检高原病易感者及在高原病康复治疗中的作用。方法采集高原世居健康者及高原病病人治疗前、后血清,用快速检测方法对应激肽含量进行测定。结果40例健康对照组应激肽含量为(77.3±16.5)mg/L,高原病病人(包括高原肺水肿和高原脑水肿病人)治疗前、后应激肽含量分别为(98.8±20.3)mg/L(、79.5±17.2)mg/L,高原病人治疗前与治疗后及健康对照组之间有显著性差异(P<0.05),治疗后应激肽含量恢复至健康水平。结论在高原病易感者人群的体液中发现低氧应激肽含量升高,经治疗后又下降至正常水平,为判断高原病病人的康复效果有一定的参考价值。

Objective To try to find out the role of the hypoxia stress paptide （HSP） in screening the crowd easy to sickness and rehabilitative treatment. Methods Collection the serum of the health and the patient of the mountain sickness pretherapy and post- treatment, detect the lISP with the fast detecting method. Results The content of the lISP of the control group and the group of the pretherapy and the group of the poet-treatment was 77.3 ±16.5mg/L,98.8 ± 20.3mg/L,79.5 ± 17.2mg/L. Conclusion The HSP was raised in the the patient of the mountain sickness, but was descent after treatment, the HSP would be reference value in judgement the effect of the treatment and rehabilitative treatment for the the patient of the mountain sickness.