期刊文献+

胰高糖素样肽-1的研究进展

下载PDF
导出
摘要 胰高糖素样肽1(GLP-1)是由胰岛α细胞和肠道神经内分泌细胞L细胞分泌的一种激素,它具有葡萄糖依赖的促胰岛素分泌和抑制胰高糖素的分泌、促进β细胞的再生和抑制细胞凋亡、降低食欲减轻体重等的作用。GLP-1的上述作用使得其在糖尿病的治疗中有广泛的应用前景。
出处 《四川医学》 CAS 2006年第5期466-468,共3页 Sichuan Medical Journal
  • 相关文献

参考文献14

  • 1冯波 李传琼.2型糖尿病血胰淀素、胰升血糖素肽水平及胰岛功能变化的探讨[J].内分泌代谢杂志,1998,14(1):44-45.
  • 2Zer M,Madsbad S,Madsen JL,et al.Effect of 6-week course of glucagon-like peptide 1 on glycaemic control,insulin sensitivity,and beta cell function in type 2 diabetes:a parallel group study[J].Lancet,2002,359:824-830.
  • 3Nauck MA,Kleine N,Orskov C,et al.Normalization of fasting hyperglycemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin dependent) diabetic patients[J].Diabetologia,1993,36:741-744.
  • 4Juhl CB,Hollingdal M,Sturis J,et al.Beditime administration of NN2211 a long-acting GLP-1 derivative,substantially reduces fasting and postprandial glycemia in type 2 diabetes[J].Diabetes,2002,51 (2):424-429.
  • 5Dunning BE,Foley JE,Ahren B.Alpha cell function in health and disease:influence of glucagon-like peptide-1[J].Diabetologia,2005,48 (9):1700-1713.
  • 6Meneilly GS,Greig N,Tildesley H,et al.Effects of 3 months of continuous subcutaneous administration of glucagon-like peptide 1 in elderly patients with type 2 diabetes[J].Diabetes Care,2003,26(10):2835-2841.
  • 7Vella A,Shah P,Basu R,et al.Effect of glucagons-like peptide 1(7-36)amide on glucose effectiveness aned insulin action people with type 2 diabetes[J].Diabetes,2000,49(4):611-617.
  • 8王毅飞,汪吉仪,王国华.胰高糖素样肽-1(7-36)NH_2引起的胰岛β细胞内游离钙变化[J].广东医学,2000,21(4):286-288. 被引量:4
  • 9王毅飞,汪吉仪,王国华.胰高糖素样肽-1(7-36)NH_2引起胰岛β细胞cAMP的变化[J].广东医学,2000,21(11):916-918. 被引量:2
  • 10Edvell A,Lindstrom P.Initiation of increased pancreatic islet growth in young normoglycemic mice (Umea +/?)[J].Endocrinology,1999,140:778-783.

二级参考文献3

共引文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部