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阿奇霉素联合头孢曲松钠治疗重症社区获得性肺炎 被引量:2

Combining azithromycin with ceftriaxone sodium for treating severity community acquired pneumonia
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摘要 目的观察阿奇霉素联合头孢曲松钠治疗重症社区获得性肺炎的临床疗效。方法随机将112例患者分为3组,A组32例,阿奇霉素针500mg/d;B组41例,头孢曲松钠针2~3g/d;C组39例,阿奇霉素针500mg/d和头孢曲松钠针2~3g/d。观察临床有效率,并对结果进行统计学分析。结果C组有效率明显高于对照组A、B。结论阿奇霉素联合头孢曲松钠治疗重症社区获得性肺炎优于上述单种抗生素。 Objective To investigate the clinicial efficacy of combining azithromycin with ceftriaxone sodium for treating severity community acquired pneumonia. Methods One hundred and twelve cases were randomly divided into three groups of thirty two patients in group A with azithromycin 500mg/d, forty one in group B with ceftriaxone sodium 2-3g/d and thirty nine in group C with azithromycin 500mg/d and ceftriaxone sodium 2-3g/d simultaneously. The clinical effective rate was observed and analyzed statistically. Results There was a better efficacy in group C than the other groups (P〈0.05). Conclusion There is a better efficacy of combining azithromycin with ceftriaxone sodium for treating severity community acquired pneumonia than azithromycin or ceftriaxone sodium used individually.
出处 《食品与药品》 CAS 2006年第05A期68-69,共2页 Food and Drug
关键词 阿奇霉素 头孢曲松钠 社区获得性肺炎 azithromycin ceftriaxone sodium community acquired pneumonia
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  • 1Pickerill KE, Paladino JA, Schentag JJ. Comparison of the fluoroquinolones based on pharmacokinetic and pharmacodynamic parameters. Pharmacotherapy, 2000,20:417-428.
  • 2Niederman MS, Mandell LA, Anzueto A, et al. Guidelines for the management of adults with community-aquired pneumonia.Diagnosis,assessment of severity, antimicrobial therapy, and provention. Am J Respir Crit Care Med, 2001,163:1730-1754.
  • 3Niederman MS. Treatment of respiratory in fections with quinolones. In: An drole V, editor, The quinolones, 2nd edition. San Diego. CA: McGraw-Hill,1998.229-250.
  • 4Bertino J Jr, Fish D. The safety profile of the fluoroquinolones. Clin Ther, 2000, 22:798-817.
  • 5Zuckerman JM, Kaye KM. The newer macrolides. Azithromycin and clarithromycin. Infect Dis Clin North Am,1995,9:713-745.
  • 6Felmingham D,Grüneberg & Alexander Project Group. Alexander Project in Europe: Decreased Susceptibility of Isolates of Stretococcus pneumoniae to Macrolides During the Perid 1992-2000. 12th ECCMID, Milan,2002. 1113.
  • 7Jacobs MR, Appelbaum & Alexander Project Group. Antimicrobial activity of several oral β-lactams, macrolides and cotrimoxazole against streptococcus pneumoniae from Japen, Singapore, Hong Kong: Alexander Project 2000. 10th Internatioal Alexander Project Congress on Infectious Disease, Singapore,2002. 138.
  • 8Heffelfinger JD, Dowell SF, Jorgensen JH,et al. Management of community-acquired pneumonia in the era of pneumococcal resistance: a report from the Drug-Resistant Streptococcus pneumoniae Therapeutic Working Group. Arch Intern Med, 2000,160:1399-1408.
  • 9Finch R. Community-acquired pneumonia: the evolving challenge. Clin Microbiol Infect, 2001,7 Suppl 3:30-38.
  • 10Lieberman D, Schlaeffer F, Boldur I, et al. Multiple pathogens in adult patients admitted with community-acquired pneumonia: a one year prospective study of 346 consecutive patients. Thorax, 1996, 51:179-184.

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