重症低钾型周期性麻痹45例临床分析

Clinical analysis for 45 patients with severe hypopotassemia periodic paralysis

目的讨论重症低钾型周期性麻痹的临床特点和治疗方法。方法45例均以肌无力急性起病,双侧基本对称;血钾平均浓度(2.02±0.45)mmol/L,心电图均有异常表现;比较在心电监测下直接补钾(A组)及在血钾结果回报后补钾(B组),监测不同时间的血钾。结果两组补钾均有效,以A组血钾恢复较快,严重并发症减少。结论重症低钾型周期性麻痹发病急、进展快,心电图和血清钾检查有助于及时诊断本病,在心电监测下,不必等血钾检查结果,静脉补钾是安全、及时和有效的。

Objective To investigate the clinical characteristic and tre.atment methods of hypopota.ssemia periodic paralysis. Methods The symptom at acute period in 45 patients was bilateral symmetric myasthenia, the average concentration of serum potassium was （2.02 ± 0.45） mmol/L, the patients had abnormal of electrocardiogram. The concentration of serum potassium treatment method and therapeutic effect in group A （directly supplying potassium under the electrocardiogram monitoring） and group B （ supplying potassium according to the result of Lab exam） were compared. Results The therapeutic effect of supplying potassium in both groups were significant, the concentration of serum potassium in group A recovered more quickly than that of group B, the incidence of serious complications in group A were less than those in group B. Conclusion The severe hypopotassemia periodic paralyses has the characteristics of acute onset, quicker progression, the electrocardiogram and concentration n of serum potassium exam can contribute to the diagnosing hypopotassemia periodic paralysis.