注射用鸦胆子油的超临界CO_2萃取工艺研究与质量评价

Study on the Supercritical Carbon Dioxide Extraction of Brucea Javanica Oil

研究注射用鸦胆子油的超临界CO2萃取工艺。考察了萃取和分离条件对鸦胆子油收率和品质的影响,探讨了萃取和分离压力等对鸦胆子油酸值的影响,确定了超临界CO2萃取鸦胆子油的最佳工艺条件。质量评价表明超临界CO2萃取工艺萃取的鸦胆子油各项指标均符合注射用精制鸦胆子油质量标准。该研究充分显示了超临界CO2萃取技术用于中药提取的优势。

The technics of supercritical carbon dioxide extraction of Brucea Javanica for injection oil was studied. The effects of the conditions of extraction and separation on extraction oil yield and quality were investigated and the effects of extraction pressure and separation pressure on acid number of the oil were discussed. So the optimal condition of this method was determined. With a quality evaluation, the Brucea Javanica oil extracted with supercritical CO2 agreed with the quality standard of refined Brucea Javanica oil for injection. This method shows sufficiently the advantages of supercritical CO2 extraction applied in the extraction of traditional Chinese medicine.